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Aplastic anaemia

Also known as: Aplastic anaemia, unspecified

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In short

Aplastic anaemia is a rare but serious blood disorder that occurs when damage to stem cells inside the bone marrow prevents it from making enough new blood cells. The condition can develop suddenly or slowly, with symptoms that can include fatigue, weakness, dizziness, shortness of breath, and easy bruising or bleeding. Causes can include autoimmune disorders, certain inherited gene changes, toxic substances, radiation therapy, chemotherapy, certain medicines, viral infections, or pregnancy, though the cause is unknown in many people. If not treated, it can lead to frequent infections, bleeding, a serious blood disorder, or heart problems such as an arrhythmia, an enlarged heart, or heart failure.

Source: MedlinePlus, National Library of Medicine.

AI-generated summary of the sources cited on this page, checked automatically against them. Not reviewed by a clinician; not medical advice.

Codes

ICD-10
D61
ICD-11
3A70.Z Aplastic anaemia, unspecified

Description

What is aplastic anemia?

Aplastic anemia is a rare but serious blood disorder. If you have it, your bone marrow doesn't make enough new blood cells. It happens when there is damage to stem cells inside your bone marrow. There are different types of aplastic anemia, including Fanconi anemia.

What causes aplastic anemia?

The causes of aplastic anemia can include:

  • Autoimmune disorders, which are the most common cause
  • Certain inherited gene changes, such as the one that can cause Fanconi anemia
  • Toxic substances, such as pesticides, arsenic, and benzene
  • Radiation therapy and chemotherapy for cancer
  • Certain medicines
  • Viral infections such as hepatitis, Epstein-Barr virus, or HIV
  • Pregnancy

In many people, the cause is unknown. This is called idiopathic aplastic anemia.

What are the symptoms of aplastic anemia?

Aplastic anemia can develop suddenly or slowly. It can be mild or severe. The symptoms of aplastic anemia can include:

  • Fatigue
  • Weakness
  • Dizziness
  • Shortness of breath
  • Easy bruising or bleeding

What other problems can aplastic anemia cause?

Aplastic anemia can cause other problems, including frequent infections and bleeding. It raises your risk of developing a serious blood disorder.

If not treated, aplastic anemia can also lead to heart problems such as an arrhythmia (a problem with the rate or rhythm of your heartbeat), an enlarged heart, or heart failure.

How is aplastic anemia diagnosed?

To find out if you have aplastic anemia, your doctor will:

  • Take your medical and your family medical histories
  • Do a physical exam
  • Order tests, such as tests to check if you have low numbers of cells in your bone marrow and blood

What are the treatments for aplastic anemia?

If you have aplastic anemia, your doctor will create a treatment plan for you. The plan will be based on how severe the anemia is and what is causing it. Treatments can include:

  • Blood transfusions
  • Blood and marrow stem cell transplants
  • Medicines to suppress your immune system

Because of the risk of blood disorders, your doctor will monitor your condition and screen you for blood disorders regularly.

NIH: National Heart, Lung, and Blood Institute

Source: MedlinePlus, National Library of Medicine.

Next to it in ICD-10

Neighbouring codes in the classification, not a medical link.

External resources

Questions

What is the ICD-10 code for Aplastic anaemia?

D61 (WHO, International Classification of Diseases, 10th Revision).

What is the ICD-11 code for Aplastic anaemia?

3A70.Z: Aplastic anaemia, unspecified (WHO, ICD-11 for Mortality and Morbidity Statistics).

Sources and attribution

  • ICD-11 for Mortality and Morbidity Statistics, © World Health Organization, licensed under CC BY-ND 3.0 IGO.
  • Names other than the official source titles: Anpheros translations and plain-language names, made with AI assistance and checked automatically; the source names are in English.
  • Source: MedlinePlus, National Library of Medicine.
  • ICD-10 codes and titles © World Health Organization. Source: WHO, International Classification of Diseases, 10th Revision (2019).

Anpheros Search catalog 2026.10.5, published 17 October 2026. About the data →