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Cushing syndrome, unspecified

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In short

Cushing's syndrome is a rare hormonal disorder caused by long-term exposure to too much cortisol, a hormone made by the adrenal gland. Taking synthetic hormone medicine to treat an inflammatory disease can lead to the disorder, or some kinds of tumors can produce a hormone that causes the body to make too much cortisol. Symptoms include upper body obesity, thin arms and legs, severe fatigue, muscle weakness, high blood pressure, high blood sugar, and easy bruising. Treatment depends on the cause of the excess cortisol and may include a lower dose of synthetic hormones or surgery and other therapies for a tumor.

Source: MedlinePlus, National Library of Medicine.

AI-generated summary of the sources cited on this page, checked automatically against them. Not reviewed by a clinician; not medical advice.

Codes

ICD-10
E24
ICD-11
5A70.Z Cushing syndrome, unspecified

Description

Cushing's syndrome is a hormonal disorder. The cause is long-term exposure to too much cortisol, a hormone that your adrenal gland makes. Sometimes, taking synthetic hormone medicine to treat an inflammatory disease leads to Cushing's. Some kinds of tumors produce a hormone that can cause your body to make too much cortisol.

Cushing's syndrome is rare. Some symptoms are:

  • Upper body obesity
  • Thin arms and legs
  • Severe fatigue and muscle weakness
  • High blood pressure
  • High blood sugar
  • Easy bruising

Lab tests can show if you have it and find the cause. Your treatment will depend on why you have too much cortisol. If it is because you have been taking synthetic hormones, a lower dose may control your symptoms. If the cause is a tumor, surgery and other therapies may be needed.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases

Source: MedlinePlus, National Library of Medicine.

Related terms in the cited sources

Medicines with an official indication for this condition

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Next to it in ICD-10

Neighbouring codes in the classification, not a medical link.

External resources

Questions

What is the ICD-10 code for Cushing syndrome, unspecified?

E24 (WHO, International Classification of Diseases, 10th Revision).

What is the ICD-11 code for Cushing syndrome, unspecified?

5A70.Z: Cushing syndrome, unspecified (WHO, ICD-11 for Mortality and Morbidity Statistics).

Sources and attribution

  • ICD-11 for Mortality and Morbidity Statistics, © World Health Organization, licensed under CC BY-ND 3.0 IGO.
  • Names other than the official source titles: Anpheros translations and plain-language names, made with AI assistance and checked automatically; the source names are in English.
  • Source: MedlinePlus, National Library of Medicine.
  • Source: European Medicines Agency (EMA) — EPAR. © European Medicines Agency.
  • ICD-10 codes and titles © World Health Organization. Source: WHO, International Classification of Diseases, 10th Revision (2019).

Anpheros Search catalog 2026.10.5, published 17 October 2026. About the data →