Histoplasmosis
Also known as: Histoplasmosis, unspecified
General information only. Anpheros does not diagnose and does not recommend treatment. Talk to a doctor or pharmacist about your situation. In an emergency, call 112 (or your local emergency number).
In short
Histoplasmosis is an infection caused by a fungus called Histoplasma, which lives in the environment, especially in soil containing large amounts of bat or bird droppings. The infection is acquired by breathing in fungal spores from the air, usually after activities that disturb the soil, and it cannot be caught from another person or an animal. Most people who breathe in the spores never have symptoms, but those who do may experience fever, cough, fatigue, chills, headache, chest pain, and body aches. Severe infections can develop into long-term lung infections or spread to other parts of the body, particularly in infants, adults age 55 and over, and people with weakened immune systems. While symptoms can go away without treatment, severe, chronic, or spread infections require prescription antifungal medicines.
Source: MedlinePlus, National Library of Medicine.
AI-generated summary of the sources cited on this page, checked automatically against them. Not reviewed by a clinician; not medical advice.
Codes
Description
What is histoplasmosis?
Histoplasmosis is an infection caused by a fungus called Histoplasma. This fungus is common in the central and eastern United States, especially around the Ohio and Mississippi River valleys. It can also be found in parts of Central and South America, Africa, Asia, and Australia. It lives in the environment, especially in soil that contains large amounts of bat or bird droppings (poop).
How do you get histoplasmosis?
You get histoplasmosis by breathing in Histoplasma fungal spores from the air. It usually happens after you have been doing an activity that disturbs the soil, such as farming, construction, and landscaping. Histoplasmosis is not contagious. This means that you cannot get the infection from another person or an animal.
What are the symptoms of histoplasmosis?
Most people who breathe in the spores never have any symptoms. If you do get symptoms, they usually start between 3 and 17 days after you breathe in the spores. The symptoms may include:
- Fever
- Cough
- Fatigue
- Chills
- Headache
- Chest pain
- Body aches
For most people, the symptoms of histoplasmosis will go away within a few weeks to a month. However, some people can have symptoms that last longer, especially if their infection becomes severe. Certain people are more likely to get a severe infection:
- People who have weakened immune systems, for example from:
- Having HIV
- Having had an organ transplant
- Taking medicines which weaken your immune system, such as chemotherapy and steroids
- Infants
- Adults age 55 and over
Severe histoplasmosis can develop into a long-term lung infection. It can also spread from the lungs to other parts of the body, such as the central nervous system (the brain and spinal cord). This is known as disseminated histoplasmosis.
How is histoplasmosis diagnosed?
To find out if you have histoplasmosis, your health care provider:
- Will ask about your symptoms and your medical and travel history
- Will do a physical exam
- Will likely order a blood, urine, or tissue test to look for signs of the fungus
- May order a chest x-ray or CT scan of the lungs
What are the treatments for histoplasmosis?
For some people, the symptoms of histoplasmosis will go away without treatment. But you will need treatment if you have severe histoplasmosis in the lungs, chronic histoplasmosis, or an infection that has spread to other parts of the body. That treatment would be with prescription antifungal medicines. In some cases, you may need to take the medicines for 3 months to 1 year.
Centers for Disease Control and Prevention
Next to it in ICD-10
- B30Viral conjunctivitis, unspecified
- B37Yeast Infections
- B38Valley Fever
- B44Aspergillosis
- B55Leishmaniasis
- B57Chagas Disease
Neighbouring codes in the classification, not a medical link.
External resources
Questions
What is the ICD-10 code for Histoplasmosis?
B39 (WHO, International Classification of Diseases, 10th Revision).
What is the ICD-11 code for Histoplasmosis?
1F2A.Z: Histoplasmosis, unspecified (WHO, ICD-11 for Mortality and Morbidity Statistics).
Sources and attribution
- ICD-11 for Mortality and Morbidity Statistics, © World Health Organization, licensed under CC BY-ND 3.0 IGO.
- Source: MedlinePlus, National Library of Medicine.
- Names other than the official source titles: Anpheros translations and plain-language names, made with AI assistance and checked automatically; the source names are in English.
- ICD-10 codes and titles © World Health Organization. Source: WHO, International Classification of Diseases, 10th Revision (2019).
Anpheros Search catalog 2026.10.5, published 17 October 2026. About the data →
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