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Hodgkin Lymphoma

Also known as: Hodgkin lymphoma, unspecified · Hodgkin Disease

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In short

Hodgkin lymphoma, also called Hodgkin disease, is a type of cancer that develops in the lymph system, which is part of the immune system. The cause of this condition is unknown, but risk factors include being male, being in early or late adulthood, having a family history of the disease, or having a past Epstein-Barr virus infection. Symptoms can include painless, swollen lymph nodes in the neck, underarm, or groin, as well as fever for no known reason, drenching night sweats, unexplained weight loss, itchy skin, and fatigue. Treatment options include chemotherapy, radiation therapy, targeted therapy, and cancer immunotherapy, and the disease can usually be cured if it is found and treated early.

Source: MedlinePlus, National Library of Medicine.

AI-generated summary of the sources cited on this page, checked automatically against them. Not reviewed by a clinician; not medical advice.

Codes

ICD-10
C81
ICD-11
2B30.Z Hodgkin lymphoma, unspecified

Description

What is Hodgkin lymphoma?

Hodgkin lymphoma, also called Hodgkin disease, is a type of cancer that develops in the lymph system. Your lymph system is part of your immune system. It helps protect your body from infection and disease.

The lymph system is made up of tissues and organs that produce, store, and carry white blood cells. It includes your:

  • Bone marrow
  • Lymph nodes
  • Lymphatic vessels
  • Spleen
  • Thymus
  • Tonsils

Hodgkin lymphoma is one of the main types of lymphoma. The other is non-Hodgkin lymphoma. Each type starts in different types of white blood cells.

What causes Hodgkin lymphoma?

The cause of Hodgkin lymphoma is unknown. But there are certain people who are at higher risk of developing it.

Who is more likely to develop Hodgkin lymphoma?

Certain factors can make you more likely to develop Hodgkin lymphoma:

  • Age. Hodgkin lymphoma is most common in early adulthood (age 20-39 years) and in late adulthood (age 65 years and older).
  • Being male. The risk of adult Hodgkin lymphoma is slightly higher in males than in females.
  • Past Epstein-Barr virus (EBV) infection. Having an infection with EBV as a young child or teenager increases your risk of Hodgkin lymphoma.
  • A family history of Hodgkin lymphoma. Having a parent or sibling with Hodgkin lymphoma increases your risk of developing it.

What are the symptoms of Hodgkin lymphoma?

The signs and symptoms of Hodgkin lymphoma may include:

  • Painless, swollen lymph nodes in the neck, underarm, or groin
  • Fever for no known reason
  • Drenching night sweats (very heavy sweating during sleep)
  • Weight loss for no known reason in the past 6 months
  • Itchy skin, especially after bathing or drinking alcohol
  • Fatigue

How is Hodgkin lymphoma diagnosed?

To find out if you have Hodgkin lymphoma, your provider:

  • Will ask about your symptoms and medical history. This will include checking for signs of disease, such as lumps or anything else that seems unusual.
  • May order some lab tests, such as:
  • Complete blood count
  • Blood chemistry studies
  • Lactate dehydrogenase (LDH) test
  • Erythrocyte sedimentation rate (ESR) test
  • Blood tests to rule out other medical conditions
  • May do imaging tests such as a CT and PET (positron emission tomography) scans
  • May do a lymph node biopsy

What are the treatments for Hodgkin lymphoma?

Treatments for Hodgkin lymphoma include:

  • Chemotherapy
  • Radiation therapy
  • Targeted therapy, which uses drugs or other substances that attack specific cancer cells with less harm to normal cells
  • Cancer immunotherapy

Hodgkin lymphoma can usually be cured if it is found and treated early.

NIH: National Cancer Institute

Source: MedlinePlus, National Library of Medicine.

Related terms in the cited sources

Medicines with an official indication for this condition

In alphabetical order.

Next to it in ICD-10

Neighbouring codes in the classification, not a medical link.

External resources

Questions

What is the ICD-10 code for Hodgkin Lymphoma?

C81 (WHO, International Classification of Diseases, 10th Revision).

What is the ICD-11 code for Hodgkin Lymphoma?

2B30.Z: Hodgkin lymphoma, unspecified (WHO, ICD-11 for Mortality and Morbidity Statistics).

Sources and attribution

  • ICD-11 for Mortality and Morbidity Statistics, © World Health Organization, licensed under CC BY-ND 3.0 IGO.
  • Source: MedlinePlus, National Library of Medicine.
  • Names other than the official source titles: Anpheros translations and plain-language names, made with AI assistance and checked automatically; the source names are in English.
  • Source: European Medicines Agency (EMA) — EPAR. © European Medicines Agency.
  • ICD-10 codes and titles © World Health Organization. Source: WHO, International Classification of Diseases, 10th Revision (2019).

Anpheros Search catalog 2026.10.5, published 17 October 2026. About the data →