Anpheros Search · Condition

Melanoma in situ neoplasms, unspecified site

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In short

Melanoma is the most serious type of skin cancer, and the first sign is often a change in the size, shape, color, or feel of a mole, or the appearance of a new, abnormal, or black mole. The "ABCDE" guide describes signs to watch for, including asymmetry, irregular borders, uneven color, changes in diameter, and evolution over weeks or months. Surgery is the first treatment of all stages of melanoma, and other treatments include chemotherapy, radiation, biologic, and targeted therapies.

Source: MedlinePlus, National Library of Medicine.

AI-generated summary of the sources cited on this page, checked automatically against them. Not reviewed by a clinician; not medical advice.

Codes

ICD-10: D03
ICD-11: 2E63.Z Melanoma in situ neoplasms, unspecified site

Description

Melanoma is the most serious type of skin cancer. Often the first sign of melanoma is a change in the size, shape, color, or feel of a mole. Most melanomas have a black or black-blue area. Melanoma may also appear as a new mole. It may be black, abnormal, or "ugly looking."
Thinking of "ABCDE" can help you remember what to watch for:
Asymmetry - the shape of one half does not match the other
Border - the edges are ragged, blurred or irregular
Color - the color is uneven and may include shades of black, brown and tan
Diameter - there is a change in size, usually an increase
Evolving - the mole has changed over the past few weeks or months
Surgery is the first treatment of all stages of melanoma. Other treatments include chemotherapy and radiation, biologic, and targeted therapies. Biologic therapy boosts your body's own ability to fight cancer. Targeted therapy uses substances that attack cancer cells without harming normal cells.
NIH: National Cancer Institute

Source: MedlinePlus, National Library of Medicine.

Next to it in ICD-10

Neighbouring codes in the classification, not a medical link.

External resources

Questions

What is the ICD-10 code for Melanoma in situ neoplasms, unspecified site?

D03 (WHO, International Classification of Diseases, 10th Revision).

What is the ICD-11 code for Melanoma in situ neoplasms, unspecified site?

2E63.Z: Melanoma in situ neoplasms, unspecified site (WHO, ICD-11 for Mortality and Morbidity Statistics).

Sources and attribution

Names other than the official source titles: Anpheros translations and plain-language names, made with AI assistance and checked automatically; the source names are in English.
Source: MedlinePlus, National Library of Medicine.
ICD-10 codes and titles © World Health Organization. Source: WHO, International Classification of Diseases, 10th Revision (2019).

Anpheros Search catalog 2026.10.5, published 17 October 2026. About the data →

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