Melanoma of the skin
Also known as: Melanoma of skin, unspecified
General information only. Anpheros does not diagnose and does not recommend treatment. Talk to a doctor or pharmacist about your situation. In an emergency, call 112 (or your local emergency number).
In short
Melanoma is the most serious type of skin cancer, and the first sign is often a change in the size, shape, color, or feel of a mole, or the appearance of a new mole. Signs to watch for include asymmetry, irregular borders, uneven color, an increase in diameter, or a mole that has evolved over the past few weeks or months. Surgery is the first treatment for all stages of melanoma, while other options include chemotherapy, radiation, biologic therapy, and targeted therapies.
Source: MedlinePlus, National Library of Medicine.
AI-generated summary of the sources cited on this page, checked automatically against them. Not reviewed by a clinician; not medical advice.
Codes
Description
Melanoma is the most serious type of skin cancer. Often the first sign of melanoma is a change in the size, shape, color, or feel of a mole. Most melanomas have a black or black-blue area. Melanoma may also appear as a new mole. It may be black, abnormal, or "ugly looking."
Thinking of "ABCDE" can help you remember what to watch for:
- Asymmetry - the shape of one half does not match the other
- Border - the edges are ragged, blurred or irregular
- Color - the color is uneven and may include shades of black, brown and tan
- Diameter - there is a change in size, usually an increase
- Evolving - the mole has changed over the past few weeks or months
Surgery is the first treatment of all stages of melanoma. Other treatments include chemotherapy and radiation, biologic, and targeted therapies. Biologic therapy boosts your body's own ability to fight cancer. Targeted therapy uses substances that attack cancer cells without harming normal cells.
NIH: National Cancer Institute
Next to it in ICD-10
- C37Thymus cancer
- C40Bone cancer of the limbs
- C41Bone cancer (other sites)
- C44Skin cancer (non-melanoma)
- C45Mesothelioma
- C46Kaposi Sarcoma
Neighbouring codes in the classification, not a medical link.
External resources
Questions
What is the ICD-10 code for Melanoma of the skin?
C43 (WHO, International Classification of Diseases, 10th Revision).
What is the ICD-11 code for Melanoma of the skin?
2C30.Z: Melanoma of skin, unspecified (WHO, ICD-11 for Mortality and Morbidity Statistics).
Sources and attribution
- ICD-11 for Mortality and Morbidity Statistics, © World Health Organization, licensed under CC BY-ND 3.0 IGO.
- Names other than the official source titles: Anpheros translations and plain-language names, made with AI assistance and checked automatically; the source names are in English.
- Source: MedlinePlus, National Library of Medicine.
- ICD-10 codes and titles © World Health Organization. Source: WHO, International Classification of Diseases, 10th Revision (2019).
Anpheros Search catalog 2026.10.5, published 17 October 2026. About the data →
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