Anpheros Search · Condition

Reactions to severe stress (including PTSD) and adjustment disorders

Also known as: Disorders specifically associated with stress, unspecified

General information only. Anpheros does not diagnose and does not recommend treatment. Talk to a doctor or pharmacist about your situation. In an emergency, call 112 (or your local emergency number).

In short

Stress is the response of the brain and body to a challenge or demand, which triggers the release of hormones that increase alertness, blood pressure, heart rate, and blood glucose levels. While short-term stress can be helpful, long-term or chronic stress lasts for weeks, months, or longer and can be caused by routine daily pressures, sudden difficult life changes, or traumatic events. Long-term stress can weaken the body's ability to fight germs, cause stomach problems, sleep issues, headaches, or emotional changes, and potentially contribute to serious health problems such as depression, anxiety, heart disease, high blood pressure, and diabetes.

Source: MedlinePlus, National Library of Medicine.

AI-generated summary of the sources cited on this page, checked automatically against them. Not reviewed by a clinician; not medical advice.

Codes

ICD-10
F43
ICD-11
6B4Z Disorders specifically associated with stress, unspecified

Description

What is stress?

Stress is how your brain and body respond to a challenge or demand. When you are stressed, your body releases certain hormones. Hormones are chemicals that travel in your bloodstream and control how different parts of your body work. The hormones that are released when you are stressed make you alert and ready to act. They can raise your blood pressure, heart rate, and blood glucose (blood sugar) levels. This response is sometimes called a "fight or flight" response.

Everyone gets stressed from time to time. There are different types of stress. It can be short-term or long-term. It can be caused by something that happens once or something that keeps happening.

Not all stress is bad. In fact, it can help you survive in a dangerous situation. For example, one kind of stress is the jolt you may feel when a car pulls out in front of you while you are driving. This jolt of hormones helps you quickly hit the brakes to avoid an accident. A little short-term stress can sometimes be helpful. For example, the stress of having a deadline for school or your job may push you to get your work done on time. Once you finish it, that stress goes away.

But stress that lasts a long time can harm your health.

What causes long-term stress?

Long-term stress, or chronic stress, lasts for weeks, months, or longer. As you go about your life, your body is acting as if you're being threatened.

Causes of long-term stress include:

  • Routine stress from the demands of work, school, family needs, money problems, and other daily pressures that don't stop.
  • Stress from sudden, difficult changes in your life, such as divorce, illness, losing your job, or other unhappy life events that often have a long impact.
  • Traumatic stress, which may happen when you're in danger of serious harm or death. Examples include being in a bad accident, a war, a flood, earthquake, or other frightening event. This type of stress can cause a long-lasting problem called post-traumatic stress disorder (PTSD).

How can long term-stress harm my health?

People respond to stress in different ways. If you're stressed for a long time you may notice that you are:

  • Getting sick more often than usual because stress weakens your body's ability to fight germs
  • Having stomach problems or trouble digesting food
  • Having trouble sleeping
  • Having headaches
  • Feeling sad, angry, or easily upset

When stress keeps going, your body acts as if you're always in danger. That's a lot of strain that may play a part in developing serious health problems, including:

  • Depression
  • Anxiety
  • Heart disease
  • High blood pressure
  • Diabetes

It's possible to get used to the symptoms of stress and not even realize there's a problem. So when there's a lot of stress in your life, it's important to pay attention to how it affects you so you can do something about it.

How can I manage long-term stress?

Simple things that improve your mental health may be helpful in managing long-term stress, such as:

  • Get regular exercise. A 30-minute daily walk can help you feel better and help keep your immune system strong, so you don't get sick.
  • Try relaxing activities. You could look for an app or wellness program that uses breathing, meditation, or muscle relaxation exercises.
  • Get enough sleep every night.
  • Avoid too much caffeine.
  • Decide what you need to do now and what can wait. And focus on what you got done each day, not on what you weren't able to do.
  • Ask your family or friends for support.

When should I ask my health care provider for help with stress?

Get help if you're having severe symptoms for 2 weeks or more, including:

  • Trouble sleeping
  • Changes in your eating that cause unwanted changes in your weight
  • Troubles getting out of bed because of your mood
  • Difficulty focusing your thoughts
  • Losing interest in things you usually enjoy
  • Not being able to do your usual daily activities

Always get help right away if stress is causing you to:

  • Have thoughts of suicide
  • Feel you can't cope
  • Use drugs or alcohol more often than usual

Your health care provider may refer you to a mental health professional such as a psychologist or social worker.

NIH: National Institute of Mental Health

Source: MedlinePlus, National Library of Medicine.

Related terms in the cited sources

Medicines with an official indication for this condition

In alphabetical order.

Next to it in ICD-10

Neighbouring codes in the classification, not a medical link.

External resources

Questions

What is the ICD-10 code for Reactions to severe stress (including PTSD) and adjustment disorders?

F43 (WHO, International Classification of Diseases, 10th Revision).

What is the ICD-11 code for Reactions to severe stress (including PTSD) and adjustment disorders?

6B4Z: Disorders specifically associated with stress, unspecified (WHO, ICD-11 for Mortality and Morbidity Statistics).

Sources and attribution

  • ICD-11 for Mortality and Morbidity Statistics, © World Health Organization, licensed under CC BY-ND 3.0 IGO.
  • Names other than the official source titles: Anpheros translations and plain-language names, made with AI assistance and checked automatically; the source names are in English.
  • Source: MedlinePlus, National Library of Medicine.
  • Source: European Medicines Agency (EMA) — EPAR. © European Medicines Agency.
  • ICD-10 codes and titles © World Health Organization. Source: WHO, International Classification of Diseases, 10th Revision (2019).

Anpheros Search catalog 2026.10.5, published 17 October 2026. About the data →