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Eptifibatide

Also known as: Eptifibatide Accord

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In short

In the European Union, eptifibatide is intended for use with acetylsalicylic acid and unfractionated heparin to prevent early myocardial infarction in adults presenting with unstable angina or non-Q-wave myocardial infarction, with the last chest pain episode within 24 hours and with electrocardiogram changes or elevated cardiac enzymes. European Union patients most likely to benefit are those at high risk of developing myocardial infarction within the first 3 to 4 days after acute angina onset, including those likely to undergo early percutaneous transluminal coronary angioplasty. In the United States, eptifibatide is a platelet aggregation inhibitor indicated to decrease the rate of a combined endpoint of death or new myocardial infarction in patients with acute coronary syndrome managed medically or with percutaneous coronary intervention. United States indications also include decreasing the rate of a combined endpoint of death, new myocardial infarction, or need for urgent intervention in patients undergoing percutaneous coronary intervention, including those undergoing intracoronary stenting.

From: Source: European Medicines Agency (EMA), Eptifibatide Accord — EPAR, 02/05/2025. © European Medicines Agency. · Data provided by the U.S. Food and Drug Administration.

AI-generated summary of the sources cited on this page, checked automatically against them. Not reviewed by a clinician; not medical advice.

Codes

RxNorm
75635 eptifibatide
EMA
EMEA/H/C/004104

Official indications

Quoted unchanged from official product information, in English. Listed alphabetically by product, not ranked.

FDA (USA) Eptifibatide

1 INDICATIONS AND USAGE Eptifibatide injection is a platelet aggregation inhibitor indicated for: Treatment of acute coronary syndrome (ACS) managed medically or with percutaneous coronary intervention (PCI). ( 1.1 ) Treatment of patients undergoing PCI (including intracoronary stenting) ( 1.2 ) 1.1 Acute Coronary Syndrome (ACS) Eptifibatide injection is indicated to decrease the rate of a combined endpoint of death or new myocardial infarction (MI) in patients with ACS (unstable angina [UA]/non-ST-elevation myocardial infarction [NSTEMI]), including patients who are to be managed medically and those undergoing percutaneous coronary intervention (PCI). 1.2 Percutaneous Coronary Intervention (PCI) Eptifibatide injection is indicated to decrease the rate of a combined endpoint of death, new MI, or need for urgent intervention in patients undergoing PCI, including those undergoing intracoronary stenting [see Clinical Studies ( 14.1 , 14.2 )] .

Data provided by the U.S. Food and Drug Administration.

Document date: 20260209 · Official document →

EMA (EU) Eptifibatide Accord

Eptifibatide Accord is intended for use with acetylsalicylic acid and unfractionated heparin. Eptifibatide Accord is indicated for the prevention of early myocardial infarction in adults presenting with unstable angina or non-Q-wave myocardial infarction, with the last episode of chest pain occurring within 24 hours and with electrocardiogram (ECG) changes and/or elevated cardiac enzymes. Patients most likely to benefit from Eptifibatide Accord treatment are those at high risk of developing myocardial infarction within the first 3-4 days after onset of acute angina symptoms including for instance those that are likely to undergo an early PTCA (Percutaneous Transluminal Coronary Angioplasty).

Source: European Medicines Agency (EMA), Eptifibatide Accord — EPAR, 02/05/2025. © European Medicines Agency.

Document date: 02/05/2025 · Official document →

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External resources

Questions

What is Eptifibatide approved for in the European Union?

Eptifibatide Accord is intended for use with acetylsalicylic acid and unfractionated heparin. Eptifibatide Accord is indicated for the prevention of early myocardial infarction in adults presenting with unstable angina or non-Q-wave myocardial infarction, with the last episode of chest pain occurring within 24 hours and with electrocardiogram (ECG) changes and/or elevated cardiac enzymes. Patients most likely to benefit from Eptifibatide Accord treatment are those at high risk of developing myocardial infarction within the first 3-4 days after onset of acute angina symptoms including for instance those that are likely to undergo an early PTCA (Percutaneous Transluminal Coronary Angioplasty). (Source: European Medicines Agency (EMA), Eptifibatide Accord — EPAR, 02/05/2025. © European Medicines Agency.)

Sources and attribution

  • Source: European Medicines Agency (EMA) — EPAR. © European Medicines Agency.
  • Names other than the official source titles: Anpheros translations and plain-language names, made with AI assistance and checked automatically; the source names are in English.
  • Data provided by the U.S. Food and Drug Administration.
  • This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.
  • Source: European Medicines Agency (EMA), Eptifibatide Accord — EPAR, 02/05/2025. © European Medicines Agency.

Anpheros Search catalog 2026.10.5, published 17 October 2026. About the data →