Lab tests

Ferritin and iron tests: serum iron, ferritin, transferrin saturation explained

The iron tests on a lab report measure different things: ferritin shows the body's iron stores, serum iron and transferrin saturation show the iron in circulation. What each test means, units and LOINC codes, and why ferritin can rise with inflammation.

by Published 3 min read

Short answer: Iron tests are a small group of blood tests: ferritin, which reflects how much iron the body has in storage; serum iron, the iron circulating in the blood; and transferrin saturation (and sometimes TIBC), which shows how much of the iron-carrying protein is loaded. Doctors read them together, often with a complete blood count.

3D illustration: a frosted glass lab report with coloured result bars and a rising trend line, a test tube with a blue cap and a drop beside it, joined by light trails

At a glance

FerritinIron in storage
Serum ironIron circulating in the blood; varies through the day
Transferrin saturationHow loaded the iron-carrying protein is
Unitsng/mL or µg/L (ferritin); µg/dL or µmol/L (iron); % (saturation)
LOINC2276-4 (ferritin), 2498-4 (iron), 2502-3 (saturation)
Read withThe complete blood count; ferritin also rises with inflammation

What the test measures

Iron is needed to make haemoglobin. Most of it is in red cells, and the rest is stored, mainly as ferritin in the liver and other tissues. A small amount of ferritin circulates in the blood and follows the size of the stores.

Serum iron changes during the day and after a meal, so on its own it says little. Transferrin is the protein that carries iron; transferrin saturation is the percentage of it that carries iron at the moment of the test.

When it is ordered

Common reasons, which your doctor adapts to you:

  • when a blood count shows anaemia or small red cells;
  • when tiredness, hair loss or heavy periods need checking;
  • to follow iron treatment, or to check for iron overload.

How the result is written on the report

Result on the report LOINC code Usual unit Also seen as
Ferritin 2276-4 ng/mL µg/L (same number)
Serum iron 2498-4 µg/dL µmol/L (×0.179)
Transferrin saturation 2502-3 % —
Haemoglobin (often on the same report) 718-7 g/dL g/L

Ferritin in ng/mL and µg/L is the same number. Serum iron in µg/dL converts with µmol/L = µg/dL × 0.179 (100 µg/dL ≈ 17.9 µmol/L).

Reading your report

Ferritin is also an 'acute-phase' protein: it rises with infection, inflammation and some liver conditions, so a normal ferritin does not always rule out low iron stores. That is why doctors may look at CRP at the same time. Serum iron is best taken in the morning and fasting, as your lab advises. Do not start or stop iron supplements based on one result without asking your doctor.

Keeping the results in your record

Scan or photograph the report in Anpheros Daily: each value is read with its unit and the laboratory's reference range, you check it, and it is stored with its LOINC code as an HL7 FHIR Observation, a format used by many hospitals and national health systems. Results from different laboratories line up on one chart over time, and the lab unit converter helps when two reports use different units. Our guide on how to read lab results explains reference ranges and flags in general; the lab results guide for a new doctor shows how to share them.

What this page does not do

It explains what the test is and how the result is written. It does not interpret your result, diagnose or recommend treatment: the meaning of a value depends on your history, your other results and how the sample was taken, and that is your doctor's job.

Sources

Frequently asked questions

What is the difference between ferritin and serum iron?

Ferritin reflects the iron stored in the body; serum iron is the iron circulating at that moment. They can point in different directions.

Can ferritin be high because of inflammation?

Yes. Infection and inflammation can raise ferritin even when iron stores are not high, which is why it is read with other results.

Is ng/mL the same as µg/L for ferritin?

Yes, the number is the same in both units.

Should I fast before an iron test?

For serum iron, labs often ask for a morning, fasting sample. Ferritin is less affected. Follow your lab's instructions.

Anpheros Daily

Try it in Anpheros Daily

Photograph your lab report and Anpheros Daily lines up each value with its reference range, so you can compare reports from different laboratories.

How it works in the app →
This guide is for information and does not replace medical advice. For decisions about your health, talk to your doctor. In an emergency, call your local emergency number (112 in Europe).
Written by
The Anpheros team

Anpheros builds a medical record that the patient controls and can share with any clinic, on an HL7 FHIR R4 platform, based in the EU. These guides help you understand and organise your health; they do not replace your doctor.

About Anpheros →
Anpheros

The more you log, the clearer your record

Your health history in one place, under your control.

Symptom diaryPatterns show over time
Emergency cardQR in your phone's Wallet
All your resultsLabs and reports together
You decideWho sees what, and for how long
Create your free account

Free · Works in your browser · No card