Lab tests

PT and INR: the blood clotting test, what it measures and why INR exists

Prothrombin time (PT) measures how long blood takes to clot; INR standardises it so results from any lab can be compared. What both numbers mean, why people on warfarin-type medicines check INR, the LOINC codes and how to keep an INR log.

by Published 3 min read

Short answer: The prothrombin time (PT) measures how many seconds a blood sample takes to clot after a reagent is added. Because reagents differ between labs, the result is converted to the INR (international normalised ratio), which can be compared anywhere. INR is checked regularly in people taking vitamin K antagonist medicines such as warfarin, and also to assess the liver's production of clotting factors.

3D illustration: a frosted glass lab report with coloured result bars and a rising trend line, a test tube with a blue cap and a drop beside it, joined by light trails

At a glance

PTSeconds a sample takes to clot after a reagent is added
INRPT converted to a ratio that can be compared between labs
Ordered forPeople on vitamin K antagonists such as warfarin; liver assessment; before surgery
LOINC5902-2 (PT), 6301-6 (INR)
Moves withDiet (vitamin K), other medicines, alcohol, illness
KeepINR with the date and the dose taken; the doctor sets the target range

What the test measures

PT reflects several clotting factors made by the liver, some of which need vitamin K. The INR is the patient's PT divided by a normal reference PT, adjusted for the sensitivity of the reagent; a person not taking anticoagulants usually has an INR around 1.

For people on vitamin K antagonists, the doctor sets a target range (often between 2 and 3, sometimes higher), and doses are adjusted to stay in it. Newer anticoagulants (DOACs) are not monitored with INR.

When it is ordered

Common reasons, which your doctor adapts to you:

  • regularly, for people taking warfarin or similar medicines;
  • before surgery or invasive procedures;
  • to assess bleeding problems or liver function.

How the result is written on the report

Result on the report LOINC code Usual unit Also seen as
INR 6301-6 ratio (no unit) —
Prothrombin time (PT) 5902-2 seconds % of normal (some countries)

INR has no unit: it is a ratio. PT is in seconds; some European labs also report it as a percentage of normal activity (Quick value), which moves in the opposite direction to the INR.

Reading your report

Your target range is personal and set by your clinician; the range printed on a general report often applies to people not taking anticoagulants. Diet (vitamin K in green vegetables), alcohol, illness and many medicines and supplements change the INR, which is why people on warfarin keep a log of results, doses and changes. Never change the dose yourself based on a result.

Keeping the results in your record

Scan or photograph the report in Anpheros Daily: each value is read with its unit and the laboratory's reference range, you check it, and it is stored with its LOINC code as an HL7 FHIR Observation, a format used by many hospitals and national health systems. Results from different laboratories line up on one chart over time, and the lab unit converter helps when two reports use different units. Our guide on how to read lab results explains reference ranges and flags in general; the lab results guide for a new doctor shows how to share them.

What this page does not do

It explains what the test is and how the result is written. It does not interpret your result, diagnose or recommend treatment: the meaning of a value depends on your history, your other results and how the sample was taken, and that is your doctor's job.

Sources

Frequently asked questions

What is the difference between PT and INR?

PT is the clotting time in seconds; INR standardises it so results from different labs are comparable.

What INR should I have?

Only your doctor can say. People not on anticoagulants are usually around 1; people on warfarin have a personal target range, often 2–3.

Do I need INR checks on newer anticoagulants?

Usually not. DOACs such as apixaban or rivaroxaban are not monitored with INR. Ask your doctor.

Can food change my INR?

Yes. Vitamin K in leafy greens, alcohol and many medicines and supplements can change it. Ask your clinic how to handle your diet, and tell them about changes in food, alcohol, medicines or supplements.

Anpheros Daily

Try it in Anpheros Daily

Photograph your lab report and Anpheros Daily lines up each value with its reference range, so you can compare reports from different laboratories.

How it works in the app →
This guide is for information and does not replace medical advice. For decisions about your health, talk to your doctor. In an emergency, call your local emergency number (112 in Europe).
Written by
The Anpheros team

Anpheros builds a medical record that the patient controls and can share with any clinic, on an HL7 FHIR R4 platform, based in the EU. These guides help you understand and organise your health; they do not replace your doctor.

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